Quentin Vicens
Email: Quentin.Vicens@cuanschutz.edu
Co-Principal Investigator on NIH R21 grant with Jeffrey Kieft, PhD, and Investigator of a 2020 RNA BioScience Initiative RNA-seq Pilot Award
"RNA never stops amazing us with intricate folds that subtly support regulatory functions. Elements within viral RNAs and retrotransposons represent a fantastic opportunity to continue capturing glimpses of how RNA operates, with relevance to biomedicine."
Quentin is a seasoned bushwhacker of the RNA jungle, having resorted to various structural and molecular biology techniques for challenging anything ribo (ribozyme, riboswitch, ribosome, ...). He is passionate about the educational process, likes to read and watch movies, cook and eat great food, and spend time with his family, especially outdoors.
Publications in the Kieft Lab
Vicens Q, Kieft JS. Shared properties and singularities of exoribonuclease-resistant RNAs in viruses. Comput Struct Biotechnol J. 2021 Jul 26;19:4373-4380.
Nichols PJ, Bevers S, Henen M, Kieft JS, Vicens Q, Vögeli B. Recognition of non-CpG repeats in Alu and ribosomal RNAs by the Z-RNA binding domain of ADAR1 induces A-Z junctions. Nat Commun. 2021 Feb 4;12(1):793.
Jones RA, Steckelberg AL, Vicens Q, Szucs MJ, Akiyama BM, Kieft JS. Different tertiary interactions create the same important 3D features in a distinct flavivirus xrRNA. RNA. 2021 Jan;27(1):54-65.
Steckelberg AL, Vicens Q, Costantino DA, Nix JC, Kieft JS. The crystal structure of a Polerovirus exoribonuclease-resistant RNA shows how diverse sequences are integrated into a conserved fold. RNA. 2020 Dec;26(12):1767-1776.
Szucs MJ, Nichols PJ, Jones RA, Vicens Q, Kieft JS. A New Subclass of Exoribonuclease-Resistant RNA Found in Multiple Genera of Flaviviridae. mBio. 2020 Sep 29;11(5):e02352-20.
Vicens Q, Kieft JS, Rissland OS. Revisiting the Closed-Loop Model and the Nature of mRNA 5'-3' Communication. Mol Cell. 2018 Dec 6;72(5):805-812.
Steckelberg AL, Vicens Q, Kieft JS. Exoribonuclease-Resistant RNAs Exist within both Coding and Noncoding Subgenomic RNAs. mBio. 2018 Dec 18;9(6):e02461-18.
For all of Q’s other publications, see his profile in ORCID